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fentanyl transmucosal and pentobarbital both of those boost sedation. Stay clear of or Use Alternate Drug. Restrict use to people for whom option cure possibilities are insufficient

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Pretreatment with or concurrent administration of phenobarbital could reduce the outcome of estradiol by raising its metabolism.

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pentobarbital and olopatadine intranasal both equally enhance sedation. Prevent or Use Alternate Drug. Coadministration boosts chance of CNS melancholy, which can result in additive impairment of psychomotor functionality and induce daytime impairment.

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pentobarbital will minimize the level or effect of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. The efficacy of hormonal contraceptives could be lowered.

pentobarbital will reduce the extent or impact of sildenafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Powerful CYP3A4 inducers are expected to result in substantial decreases in sildenafil plasma concentrations

pentobarbital will reduce the extent or influence of ethinylestradiol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. The efficacy of hormonal contraceptives may be lessened. Utilization of a nonhormonal contraceptive is recommended.

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